Omega-6 to Omega-3 Ratio
Definition
The proportion of omega-6 polyunsaturated fatty acids (pro-inflammatory, e.g., linoleic acid) to omega-3 polyunsaturated fatty acids (anti-inflammatory, e.g., EPA and DHA) in the diet or in a specific oil/food. Both are essential fatty acids, but their balance determines inflammatory status.
Why It Matters
Ancestral human diets had an omega-6:3 ratio of approximately 1:1 to 4:1. The modern Western diet, dominated by seed oils and processed foods, has shifted this ratio to 15:1 to 20:1. This extreme imbalance is a major driver of chronic inflammation — the underlying mechanism behind cardiovascular disease, autoimmune conditions, obesity, and depression. Reducing omega-6 intake (primarily from seed oils) is as important as increasing omega-3 intake.